Transient receptor potential vanilloid 1 and 4 double knockout leads to increased bone mass in mice.

Nishimura, Haruki; Kawasaki, Makoto; Tsukamoto, Manabu; Menuki, Kunitaka; Suzuki, Hitoshi; Matsuura, Takanori; Baba, Kazuhiko; Motojima, Yasuhito; Fujitani, Teruaki; Ohnishi, Hideo; Yamanaka, Yoshiaki; Kosugi, Kenji; Okada, Yasuaki; Tokuda, Kotaro; Tajima, Takafumi; Yoshioka, Toru; Okimoto, Nobukazu; Ueta, Yoichi; Sakai, Akinori

Nishimura, Haruki; Kawasaki, Makoto; Tsukamoto, Manabu; Menuki, Kunitaka; Suzuki, Hitoshi; Matsuura, Takanori; Baba, Kazuhiko; Motojima, Yasuhito; Fujitani, Teruaki; Ohnishi, Hideo; Yamanaka, Yoshiaki; Kosugi, Kenji; Okada, Yasuaki; Tokuda, Kotaro; Tajima, Takafumi; Yoshioka, Toru; Okimoto, Nobukazu; Ueta, Yoichi; Sakai, Akinori.

Afiliação

Nishimura H; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Kawasaki M; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Tsukamoto M; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Menuki K; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Suzuki H; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Matsuura T; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Baba K; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Motojima Y; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Fujitani T; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Ohnishi H; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Yamanaka Y; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Kosugi K; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Okada Y; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Tokuda K; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Tajima T; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Yoshioka T; Department of Orthopaedics, Shimura Hospital, 3-13 Funairimachi Naka-ku, Hiroshima 730-0841, Japan.
Okimoto N; Okimoto Clinic, 185-4 Yutakamachikubi, Kure, Hiroshima 734-0304, Japan.
Ueta Y; Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Sakai A; Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.

Bone Rep ; 12: 100268, 2020 Jun.

Article em En | MEDLINE | ID: mdl-32373678

Palavras-chave

ALP, alkaline phosphatase; BMD, bone mineral density; BMSCs, bone marrow mesenchymal stem cells; Bone histomorphometry; CB, cannabinoid; CT, computed tomography; Cell culture; DKO, double knock out; DXA, dual-energy X-ray absorption; MNCs, multinucleated cells; Micro-CT; Osteogenesis; PCR, polymerase chain reaction; POc, preosteoclast; Preosteoclast; RANK, receptor activator of nuclear factor-kappa B; RANKL, receptor activator of nuclear factor-kappa B ligand; TRACP, tartrate-resistant acid phosphatase; TRPV, transient receptor potential vanilloid; Transient receptor potential vanilloid; V1KO, TRPV1 knock out; V4KO, TRPV4 knock out; WT, wild type

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Bone Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google