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HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection.
Bodda, Chiranjeevi; Reinert, Line S; Fruhwürth, Stefanie; Richardo, Timmy; Sun, Chenglong; Zhang, Bao-Cun; Kalamvoki, Maria; Pohlmann, Anja; Mogensen, Trine H; Bergström, Petra; Agholme, Lotta; O'Hare, Peter; Sodeik, Beate; Gyrd-Hansen, Mads; Zetterberg, Henrik; Paludan, Søren R.
Afiliação
  • Bodda C; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Reinert LS; Nuffield Department of Medicine, Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK.
  • Fruhwürth S; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Richardo T; Department of Rheumatology and Inflammation Research, Institute of Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Sun C; Institute of Virology, Hannover Medical School, Hannover, Germany.
  • Zhang BC; Cluster of Excellence Resolving Infection Susceptibility, Hannover Medical School, Hannover, Germany.
  • Kalamvoki M; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Pohlmann A; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Mogensen TH; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics, and Immunology, Kansas City, KS.
  • Bergström P; Institute of Virology, Hannover Medical School, Hannover, Germany.
  • Agholme L; Cluster of Excellence Resolving Infection Susceptibility, Hannover Medical School, Hannover, Germany.
  • O'Hare P; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Sodeik B; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Gyrd-Hansen M; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
  • Zetterberg H; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Paludan SR; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
J Exp Med ; 217(7)2020 07 06.
Article em En | MEDLINE | ID: mdl-32383759

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Encéfalo / Interferon Tipo I / Herpesvirus Humano 1 / Enzimas Desubiquitinantes / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: J Exp Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Encéfalo / Interferon Tipo I / Herpesvirus Humano 1 / Enzimas Desubiquitinantes / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: J Exp Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Estados Unidos