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Cardiac surgery in patients with Hemophilia:is it safe?
Shalabi, Amjad; Kachel, Erez; Kogan, Alexander; Sternik, Leonid; Grosman-Rimon, Liza; Ben-Avi, Ronny; Ghanem, Diab; Ram, Eilon; Raanani, Ehud; Misgav, Mudi.
Afiliação
  • Shalabi A; Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel. amjadra3008@gmail.com.
  • Kachel E; Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel. amjadra3008@gmail.com.
  • Kogan A; Cardiovascular Department and Research Center, Poriya Medical Center, 15208, Tiberias, Israel. amjadra3008@gmail.com.
  • Sternik L; affiliated to the Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel. amjadra3008@gmail.com.
  • Grosman-Rimon L; Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel.
  • Ben-Avi R; Cardiovascular Department and Research Center, Poriya Medical Center, 15208, Tiberias, Israel.
  • Ghanem D; affiliated to the Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
  • Ram E; Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel.
  • Raanani E; Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel.
  • Misgav M; Cardiovascular Department and Research Center, Poriya Medical Center, 15208, Tiberias, Israel.
J Cardiothorac Surg ; 15(1): 76, 2020 05 08.
Article em En | MEDLINE | ID: mdl-32384896
BACKGROUND: The life expectancy of hemophiliacs is similar to that of the general population. As a result, the prevalence of age-related cardiovascular diseases has increased. We present our experience with hemophilia patients who underwent cardiac surgery in our Medical Center between 2004 and 2019. METHODS: All hemophilia patients who underwent cardiac surgery were identified, and their peri-operative data evaluated retrospectively. RESULTS: Ten patients were identified: six with hemophilia-A, one with hemophilia-B, and three with hemophilia-C (factor XI deficiency). Cardiac procedures included ten coronary artery bypass grafts and one aortic valve replacement. Hemophilia-A and B patients were treated with factor substitution, whereas patients with factor XI deficiency were treated with fresh frozen plasma. One patient died, and one patient suffered from non-active gastrointestinal bleeding. CONCLUSIONS: While major cardiac surgery can be performed safely on patients with hemophilia, a multidisciplinary team approach and strict postoperative monitoring are essential in order to achieve optimal results.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemofilia B / Deficiência do Fator XI / Cardiopatias / Procedimentos Cirúrgicos Cardíacos / Hemofilia A Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cardiothorac Surg Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Israel País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemofilia B / Deficiência do Fator XI / Cardiopatias / Procedimentos Cirúrgicos Cardíacos / Hemofilia A Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cardiothorac Surg Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Israel País de publicação: Reino Unido