The immune response to a recombinant Lactococcus lactis oral vaccine against foot-and-mouth disease virus in mice.

Liu, Xinsheng; Qi, Linlin; Lv, Jianliang; Zhang, Zhongwang; Zhou, Peng; Ma, Zhongyuan; Wang, Yonglu; Zhang, Yongguang; Pan, Li

Liu, Xinsheng; Qi, Linlin; Lv, Jianliang; Zhang, Zhongwang; Zhou, Peng; Ma, Zhongyuan; Wang, Yonglu; Zhang, Yongguang; Pan, Li.

Afiliação

Liu X; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Qi L; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Lv J; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Zhang Z; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China. zhangzhongwang@caas.cn.
Zhou P; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Ma Z; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Wang Y; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Zhang Y; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Pan L; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.

Biotechnol Lett ; 42(10): 1907-1917, 2020 Oct.

Article em En | MEDLINE | ID: mdl-32385744

Assuntos

Febre Aftosa; Lactococcus lactis/genética; Vacinas de DNA; Vacinas Virais; Administração Oral; Animais; Anticorpos Antivirais/sangue; Proteínas do Capsídeo/genética; Proteínas do Capsídeo/imunologia; Proteínas do Capsídeo/metabolismo; Citocinas/sangue; Feminino; Febre Aftosa/imunologia; Febre Aftosa/prevenção & controle; Vírus da Febre Aftosa/imunologia; Imunidade nas Mucosas/imunologia; Camundongos; Camundongos Endogâmicos BALB C; Vacinas de DNA/administração & dosagem; Vacinas de DNA/genética; Vacinas de DNA/imunologia; Vacinas Virais/administração & dosagem; Vacinas Virais/genética; Vacinas Virais/imunologia

Palavras-chave

Foot-and-mouth disease virus; Lactococcus lactis; Mucosal immunity; Oral vaccine; VP1 protein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Lactococcus lactis / Vacinas de DNA / Febre Aftosa Limite: Animals Idioma: En Revista: Biotechnol Lett Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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