Emergence of prions selectively resistant to combination drug therapy.

Burke, Cassandra M; Mark, Kenneth M K; Kun, Judit; Beauchemin, Kathryn S; Supattapone, Surachai

Burke, Cassandra M; Mark, Kenneth M K; Kun, Judit; Beauchemin, Kathryn S; Supattapone, Surachai.

Afiliação

Burke CM; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Mark KMK; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Kun J; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Beauchemin KS; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Supattapone S; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.

PLoS Pathog ; 16(5): e1008581, 2020 05.

Article em En | MEDLINE | ID: mdl-32421750

Assuntos

Benzodioxóis/farmacologia; Proteínas PrPSc/metabolismo; Pirazóis/farmacologia; Scrapie/tratamento farmacológico; Animais; Quimioterapia Combinada; Camundongos; Proteínas PrPSc/patogenicidade; Scrapie/metabolismo; Scrapie/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Scrapie / Proteínas PrPSc / Benzodioxóis Limite: Animals Idioma: En Revista: PLoS Pathog Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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