Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription.

Sorino, Cristina; Catena, Valeria; Bruno, Tiziana; De Nicola, Francesca; Scalera, Stefano; Bossi, Gianluca; Fabretti, Francesca; Mano, Miguel; De Smaele, Enrico; Fanciulli, Maurizio; Iezzi, Simona

Sorino, Cristina; Catena, Valeria; Bruno, Tiziana; De Nicola, Francesca; Scalera, Stefano; Bossi, Gianluca; Fabretti, Francesca; Mano, Miguel; De Smaele, Enrico; Fanciulli, Maurizio; Iezzi, Simona.

Afiliação

Sorino C; SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Catena V; Department of Experimental Medicine, Sapienza-University of Rome, 00161 Rome, Italy.
Bruno T; SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
De Nicola F; SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Scalera S; SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Bossi G; SAFU Laboratory, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Fabretti F; Oncogenomic and Epigenetic Unit, Department of Research, Advanced Diagnostics and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Mano M; Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital of Cologne, 50937 Cologne, Germany.
De Smaele E; CECAD, University of Cologne, Faculty of Medicine and University Hospital of Cologne, 50931 Cologne, Germany.
Fanciulli M; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra 3060 197, Portugal.
Iezzi S; Department of Experimental Medicine, Sapienza-University of Rome, 00161 Rome, Italy.

Nucleic Acids Res ; 48(11): 5891-5906, 2020 06 19.

Article em En | MEDLINE | ID: mdl-32421830

Assuntos

Proteínas Reguladoras de Apoptose/metabolismo; DNA Ribossômico/genética; Genes de RNAr/genética; RNA Polimerase I/metabolismo; Proteínas Repressoras/metabolismo; Transcrição Gênica; Proteínas Reguladoras de Apoptose/deficiência; Proteínas Reguladoras de Apoptose/genética; Proteínas Mutadas de Ataxia Telangiectasia/metabolismo; Pontos de Checagem do Ciclo Celular; Linhagem Celular; Nucléolo Celular/metabolismo; Nucléolo Celular/patologia; Dano ao DNA; DNA Ribossômico/metabolismo; Homeostase; Humanos; Fosforilação; Proteínas Pol1 do Complexo de Iniciação de Transcrição/metabolismo; Regiões Promotoras Genéticas; Proteínas Repressoras/deficiência; Proteínas Repressoras/genética; Ribossomos/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Transcrição Gênica / RNA Polimerase I / DNA Ribossômico / Genes de RNAr / Proteínas Reguladoras de Apoptose Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália País de publicação: Reino Unido

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