Hemoptysis as the first symptom in the diagnosis of metastatic choriocarcinoma in the third trimester of pregnancy: A case report.
Case Rep Womens Health
; 27: e00211, 2020 Jul.
Article
em En
| MEDLINE
| ID: mdl-32426244
ABSTRACT
INTRODUCTION:
Choriocarcinoma is a rare neoplasm (1/40000 pregnancies). In the context of a viable pregnancy, the incidence is even lower (1/160000). CASE REPORT A woman in her second pregnancy was admitted at 31â¯+â¯6â¯weeks of gestation with hemoptysis and abnormal vaginal bleeding. Numerous placental venous lakes, bilateral pulmonary nodules and a pleural effusion were found. Pleural fluid ß-HCG levels were elevated and a brain-chest-abdominal-pelvic CT scan led to the diagnosis of a high-risk gestational trophoblastic neoplasm. A caesarean section at 32â¯+â¯1â¯weeks of gestation was performed. Six cycles of an EMA-CO chemotherapy regime were administered. ß-HCG levels normalized after 3â¯cycles. Placental histopathology confirmed the presence of a gestational choriocarcinoma.CONCLUSION:
Choriocarcinoma is a highly aggressive tumor. In high-risk tumors, combination chemotherapy is the first-line treatment, offering high remission rates. Treatment response is evaluated by monitoring blood ß-HCG levels, which should be long-term.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Case Rep Womens Health
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Espanha