Interstitial glucose and subsequent affective and physical feeling states: A pilot study combining continuous glucose monitoring and ecological momentary assessment in adolescents.
J Psychosom Res
; 135: 110141, 2020 08.
Article
em En
| MEDLINE
| ID: mdl-32447156
ABSTRACT
OBJECTIVE:
Circulating glucose may relate to affective and physical feeling states reflective of emotional disorder symptoms. No prior studies have investigated within-day associations between glucose and subsequent affective and physical feeling states (positive affect, negative affect, and fatigue) as they occur naturally among healthy adolescents; this pilot study assessed these associations by combining data collected from ecological momentary assessment (EMA) and continuous glucose monitors (CGM).METHODS:
Participants (N = 15, mean age = 13.1[±1.0] years, 66.7% female, 40.0% Hispanic, 66.7% healthy weight) wore a CGM for 7-14 days. Simultaneously, participants reported on their current positive affect, negative affect, and fatigue randomly during specified windows up to 7 times daily via EMA. CGM-measured mean interstitial glucose was calculated during the time windows (mean minutes = 122.5[±47.3]) leading up to each EMA prompt. Multilevel models assessed within-subject (WS) associations between mean interstitial glucose since the previous EMA prompt and EMA-reported affective and physical feeling states at the current prompt.RESULTS:
Participants provided 532 interstitial glucose-matched EMA reports of affective and physical feeling states. During intervals when interstitial glucose was higher than one's usual, higher positive affect (WS ß = 0.01, p < .0001, f2 = 0.02) and lower fatigue (WS ß = -0.01, p < .0001, f2 = 0.09) were subsequently reported. Interstitial glucose was unrelated to negative affect (WS ß = -0.002, p = .10, f2 = 0.01). Associations were weakened, but remained significant following further adjustment for time of day.CONCLUSIONS:
Though effect sizes were small, within-person variations in interstitial glucose may relate to subsequent affective and physical feeling states among healthy youth. Investigations using similar methodologies in larger, more diverse samples are warranted.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Automonitorização da Glicemia
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Avaliação Momentânea Ecológica
Limite:
Adolescent
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Female
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Humans
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Male
Idioma:
En
Revista:
J Psychosom Res
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Estados Unidos