Doxorubicin contributes to thrombus formation and vascular injury by interfering with platelet function.

Lv, Haichen; Tan, Ruopeng; Liao, Jiawei; Hao, Zhujing; Yang, Xiaolei; Liu, Yang; Xia, Yunlong

Lv, Haichen; Tan, Ruopeng; Liao, Jiawei; Hao, Zhujing; Yang, Xiaolei; Liu, Yang; Xia, Yunlong.

Afiliação

Lv H; Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Tan R; Institute of Cardiovascular Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Liao J; Institute of Cardiovascular Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Hao Z; Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yang X; Institute of Cardiovascular Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Liu Y; Institute of Cardiovascular Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xia Y; Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Am J Physiol Heart Circ Physiol ; 319(1): H133-H143, 2020 07 01.

Article em En | MEDLINE | ID: mdl-32469636

Assuntos

Antineoplásicos/toxicidade; Plaquetas/efeitos dos fármacos; Doxorrubicina/toxicidade; Endotélio Vascular/efeitos dos fármacos; Trombose/etiologia; Animais; Antineoplásicos/farmacologia; Plaquetas/fisiologia; Células Cultivadas; Doxorrubicina/farmacologia; Feminino; Camundongos; Camundongos Endogâmicos C57BL; Agregação Plaquetária

Palavras-chave

cardio-oncology; doxorubicin; platelets; thrombosis; vascular injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Plaquetas / Endotélio Vascular / Doxorrubicina / Antineoplásicos Limite: Animals Idioma: En Revista: Am J Physiol Heart Circ Physiol Assunto da revista: CARDIOLOGIA / FISIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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