Effect of add-on transcranial alternating current stimulation (tACS) on persistent delusions in schizophrenia.
Psychiatry Res
; 290: 113106, 2020 08.
Article
em En
| MEDLINE
| ID: mdl-32474070
ABSTRACT
The utility of non-invasive brain stimulation techniques to alleviate resistant delusions in schizophrenia is an under-researched area. In this study, we report the effectiveness of alpha transcranial alternating current stimulation (tACS) targeting the medial prefrontal cortex in ameliorating persistent delusions. Twelve Schizophrenia patients (N=12) with persistent delusions received add-on treatment with a twice-daily 20-minutes session of 10-Hz tACS. Significant reduction in severity of delusion was noted after 5th day (z=2.67, p<0.01, n=12) with further improvement after 10th day (z=2.52, p=0.01, n=9) of stimulation. Add-on treatment with 10-Hz tACS is a potential therapeutic option for treatment-resistant delusions, which requires further systematic research.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Delusões
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Estimulação Transcraniana por Corrente Contínua
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Psychiatry Res
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Índia