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Functional State of Mesenchymal Stem Cells upon Exposure to Bioactive Coatings on Titanium Alloys.
Plekhova, N G; Lyapun, I N; Drobot, E I; Shevchuk, D V; Sinebryukhov, S L; Mashtalyar, D V; Gnedenkov, S V.
Afiliação
  • Plekhova NG; Central Research Laboratory, Pacific State Medical University, the Ministry of Health of the Russian Federation, Vladivostok, Russia. pl_nat@hotmail.com.
  • Lyapun IN; G. P. Somov Research Institute Epidemiology and Microbiology, Vladivostok, Russia.
  • Drobot EI; G. P. Somov Research Institute Epidemiology and Microbiology, Vladivostok, Russia.
  • Shevchuk DV; Central Research Laboratory, Pacific State Medical University, the Ministry of Health of the Russian Federation, Vladivostok, Russia.
  • Sinebryukhov SL; Institute of Chemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia.
  • Mashtalyar DV; Institute of Chemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia.
  • Gnedenkov SV; Institute of Chemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia.
Bull Exp Biol Med ; 169(1): 147-156, 2020 May.
Article em En | MEDLINE | ID: mdl-32488788
Bioactive coatings on implants affect osteogenic differentiation of mesenchymal stem cells (MSC). We studied the morphofunctional state of bone marrow MSC cultured on the surface of calcium phosphate coatings on titanium formed by plasma electrolytic oxidation (PEO). The biocompatible properties of the coatings manifested in the absence of the cytotoxic effect on cells. High expression of receptors (CD90, CD29, and CD106), enhanced synthesis of osteocalcin and osteopontin, and changes in surface architectonics of MSC adherent to the samples confirmed osteoinductive properties of the calcium phosphate PEO coating.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Titânio / Materiais Revestidos Biocompatíveis / Células-Tronco Mesenquimais Limite: Animals Idioma: En Revista: Bull Exp Biol Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Titânio / Materiais Revestidos Biocompatíveis / Células-Tronco Mesenquimais Limite: Animals Idioma: En Revista: Bull Exp Biol Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Estados Unidos