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The Legionella kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Lee, Pei-Chung; Beyrakhova, Ksenia; Xu, Caishuang; Boniecki, Michal T; Lee, Mitchell H; Onu, Chisom J; Grishin, Andrey M; Machner, Matthias P; Cygler, Miroslaw.
Afiliação
  • Lee PC; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892.
  • Beyrakhova K; Department of Biological Sciences, College of Liberal Arts and Sciences, Wayne State University, Detroit, MI 48202.
  • Xu C; Department of Biochemistry, University of Saskatchewan, Saskatoon, SK S7N5E5, Canada.
  • Boniecki MT; Department of Biochemistry, University of Saskatchewan, Saskatoon, SK S7N5E5, Canada.
  • Lee MH; Department of Biochemistry, University of Saskatchewan, Saskatoon, SK S7N5E5, Canada.
  • Onu CJ; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892.
  • Grishin AM; Department of Biological Sciences, College of Liberal Arts and Sciences, Wayne State University, Detroit, MI 48202.
  • Machner MP; Department of Biochemistry, University of Saskatchewan, Saskatoon, SK S7N5E5, Canada.
  • Cygler M; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892; machnerm@nih.gov miroslaw.cygler@usask.ca.
Proc Natl Acad Sci U S A ; 117(25): 14433-14443, 2020 06 23.
Article em En | MEDLINE | ID: mdl-32513747

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Proteínas de Bactérias / Legionella pneumophila / Peptídeos e Proteínas de Sinalização Intracelular / Proteínas Adaptadoras de Transdução de Sinal Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Proteínas de Bactérias / Legionella pneumophila / Peptídeos e Proteínas de Sinalização Intracelular / Proteínas Adaptadoras de Transdução de Sinal Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos