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Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent.
Pindiprolu, Sai Kiran S S; Kumar, Chirravuri S Phani; Kumar Golla, Venu Sampath; P, Likitha; K, Shreyas Chandra; S K, Esub Basha; R K, Ramachandra.
Afiliação
  • Pindiprolu SKSS; Adarsa College of Pharmacy, East Godavari, Andhra Pradesh, India.
  • Kumar CSP; Adarsa College of Pharmacy, East Godavari, Andhra Pradesh, India.
  • Kumar Golla VS; A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh, India.
  • P L; A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh, India.
  • K SC; Adhra Medical College, Visakhapatnam, Andhra Pradesh, India. Electronic address: shreyaschandrak@gmail.com.
  • S K EB; Crystal Growth and Nano-Science Research Center, Government College(A), Rajahmundry, Andhra Pradesh, India. Electronic address: esubinanu2005@gmail.com.
  • R K R; Crystal Growth and Nano-Science Research Center, Government College (A), Rajahmundry, Andhra Pradesh, India. Electronic address: ramc@gcrjy.ac.in.
Med Hypotheses ; 143: 109858, 2020 Oct.
Article em En | MEDLINE | ID: mdl-32516655
ABSTRACT
Coronavirus disease outbreak caused a severe public health burden all over the world. Salinomycin (SAL) is a broad-spectrum antibiotic that had drawn attention in selective targeting of cancer and viral infections. Recent drug screen identified SAL as a potent antiviral agent against SARS-CoV-2. In this hypothesis, we discuss the potential of pulmonary delivery of SAL using nanostructured lipid carriers (NLCs) against SARS-CoV-2.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pneumonia Viral / Piranos / Portadores de Fármacos / Infecções por Coronavirus / Nanoestruturas / Lipídeos Limite: Humans Idioma: En Revista: Med Hypotheses Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Índia
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pneumonia Viral / Piranos / Portadores de Fármacos / Infecções por Coronavirus / Nanoestruturas / Lipídeos Limite: Humans Idioma: En Revista: Med Hypotheses Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Índia