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A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.
Narayan, Ravi S; Molenaar, Piet; Teng, Jian; Cornelissen, Fleur M G; Roelofs, Irene; Menezes, Renee; Dik, Rogier; Lagerweij, Tonny; Broersma, Yoran; Petersen, Naomi; Marin Soto, Jhon Alexander; Brands, Eelke; van Kuiken, Philip; Lecca, Maria C; Lenos, Kristiaan J; In 't Veld, Sjors G J G; van Wieringen, Wessel; Lang, Frederick F; Sulman, Erik; Verhaak, Roel; Baumert, Brigitta G; Stalpers, Lucas J A; Vermeulen, Louis; Watts, Colin; Bailey, David; Slotman, Ben J; Versteeg, Rogier; Noske, David; Sminia, Peter; Tannous, Bakhos A; Wurdinger, Tom; Koster, Jan; Westerman, Bart A.
Afiliação
  • Narayan RS; Department of Radiation Oncology, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Molenaar P; Department of Oncogenomics, Academic Medical Center, Amsterdam, the Netherlands.
  • Teng J; Experimental Therapeutics and Molecular Imaging Lab, Neuroscience Center, Neuro-Oncology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Cornelissen FMG; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Roelofs I; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Menezes R; Department of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Dik R; Department of Radiation Oncology, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Lagerweij T; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Broersma Y; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Petersen N; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Marin Soto JA; Department of Medical Oncology, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Brands E; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • van Kuiken P; Department of Hematology, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Lecca MC; Department of Radiation Oncology, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Lenos KJ; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • In 't Veld SGJG; Center for Experimental Molecular Medicine (CEMM), Laboratory for Experimental Oncology and Radiobiology (LEXOR), Amsterdam UMC, location AMC, Cancer Center, Amsterdam, the Netherlands.
  • van Wieringen W; Center for Experimental Molecular Medicine (CEMM), Laboratory for Experimental Oncology and Radiobiology (LEXOR), Amsterdam UMC, location AMC, Cancer Center, Amsterdam, the Netherlands.
  • Lang FF; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Sulman E; Department of Epidemiology and Biostatistics, Amsterdam UMC, location VUMC, Amsterdam, the Netherlands.
  • Verhaak R; Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Baumert BG; Department of Radiation Oncology, NYU Langone Health, New York, NY, 10016, USA.
  • Stalpers LJA; Department of Computational Biology, The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
  • Vermeulen L; Department of Radio-Oncology, Kantonsspital Graubünden, Loëstrasse 170, CH-7000, Chur, Switzerland.
  • Watts C; Radiation Oncology, Academic Medical Center, Amsterdam, the Netherlands.
  • Bailey D; Center for Experimental Molecular Medicine (CEMM), Laboratory for Experimental Oncology and Radiobiology (LEXOR), Amsterdam UMC, location AMC, Cancer Center, Amsterdam, the Netherlands.
  • Slotman BJ; Neurosurgery, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
  • Versteeg R; IOTA Pharmaceuticals Ltd, St Johns Innovation Centre, Cowley Road, Cambridge, UK.
  • Noske D; Department of Radiation Oncology, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Sminia P; Department of Oncogenomics, Academic Medical Center, Amsterdam, the Netherlands.
  • Tannous BA; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Wurdinger T; Department of Radiation Oncology, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
  • Koster J; Experimental Therapeutics and Molecular Imaging Lab, Neuroscience Center, Neuro-Oncology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Westerman BA; Department of Neurosurgery, Amsterdam UMC, location VUMC, Cancer Center, Amsterdam, the Netherlands.
Nat Commun ; 11(1): 2935, 2020 06 10.
Article em En | MEDLINE | ID: mdl-32523045
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinergismo Farmacológico Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinergismo Farmacológico Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido