Light-assisted hierarchical intratumoral penetration and programmed antitumor therapy based on tumor microenvironment (TME)-amendatory and self-adaptive polymeric nanoclusters.

Yan, Jing; Wu, Qinghua; Zhao, Ziyin; Wu, Jianhua; Ye, Huan; Liang, Qiujun; Zhou, Zhuchao; Hou, Mengying; Li, Xudong; Liu, Yong; Yin, Lichen

Yan, Jing; Wu, Qinghua; Zhao, Ziyin; Wu, Jianhua; Ye, Huan; Liang, Qiujun; Zhou, Zhuchao; Hou, Mengying; Li, Xudong; Liu, Yong; Yin, Lichen.

Afiliação

Yan J; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China.
Wu Q; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China.
Zhao Z; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China.
Wu J; Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Ye H; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China.
Liang Q; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China.
Zhou Z; Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China. Electronic address: zhouzhuchao@hotmail.com.
Hou M; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China.
Li X; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China.
Liu Y; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China. Electronic address: liuyong1987@suda.edu.cn.
Yin L; Jiangsu Key Laboratory of Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, 215123, China. Electronic address: lcyin@suda.edu.cn.

Biomaterials ; 255: 120166, 2020 10.

Article em En | MEDLINE | ID: mdl-32544718

Assuntos

Nanomedicina; Microambiente Tumoral; Linhagem Celular Tumoral; Polímeros

Palavras-chave

Cancer-associated fibroblasts (CAFs); Light-responsiveness; Photodynamic therapy (PDT); Size reduction; Stroma depletion; Tumor penetration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanomedicina / Microambiente Tumoral Idioma: En Revista: Biomaterials Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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