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Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.
Qiao, Xiaohang; van der Zanden, Sabina Y; Wander, Dennis P A; Borràs, Daniel M; Song, Ji-Ying; Li, Xiaoyang; van Duikeren, Suzanne; van Gils, Noortje; Rutten, Arjo; van Herwaarden, Tessa; van Tellingen, Olaf; Giacomelli, Elisa; Bellin, Milena; Orlova, Valeria; Tertoolen, Leon G J; Gerhardt, Sophie; Akkermans, Jimmy J; Bakker, Jeroen M; Zuur, Charlotte L; Pang, Baoxu; Smits, Anke M; Mummery, Christine L; Smit, Linda; Arens, Ramon; Li, Junmin; Overkleeft, Hermen S; Neefjes, Jacques.
Afiliação
  • Qiao X; Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands; x.qiao@nki.nl drlijunmin@126.com j.j.c.neefjes@lumc.nl.
  • van der Zanden SY; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Wander DPA; Department of Cell and Chemical Biology, ONCODE Institute, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Borràs DM; Leiden Institute of Chemistry, Leiden University, 2300 RA Leiden, The Netherlands.
  • Song JY; Department of Cell and Chemical Biology, ONCODE Institute, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Li X; Division of Experimental Animal Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • van Duikeren S; Department of Hematology, Shanghai Institute of Hematology, National Research Center for Translational Medicine, RuiJin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 200025 Shanghai, China.
  • van Gils N; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • Rutten A; Department of Hematology, Vrije Universiteit Medical Center, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands.
  • van Herwaarden T; Department of Hematology, Vrije Universiteit Medical Center, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands.
  • van Tellingen O; Department of Cell and Chemical Biology, ONCODE Institute, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Giacomelli E; Division of Diagnostic Oncology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Bellin M; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Orlova V; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Tertoolen LGJ; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Gerhardt S; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Akkermans JJ; Central Laboratory Animal Facility, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Bakker JM; Department of Cell and Chemical Biology, ONCODE Institute, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Zuur CL; Department of Cell and Chemical Biology, ONCODE Institute, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Pang B; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Smits AM; Department of Cell and Chemical Biology, ONCODE Institute, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Mummery CL; Department of Cell and Chemical Biology, ONCODE Institute, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Smit L; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
  • Arens R; Department of Hematology, Vrije Universiteit Medical Center, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands.
  • Li J; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • Overkleeft HS; Department of Hematology, Shanghai Institute of Hematology, National Research Center for Translational Medicine, RuiJin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 200025 Shanghai, China; x.qiao@nki.nl drlijunmin@126.com j.j.c.neefjes@lumc.nl.
  • Neefjes J; Leiden Institute of Chemistry, Leiden University, 2300 RA Leiden, The Netherlands.
Proc Natl Acad Sci U S A ; 117(26): 15182-15192, 2020 06 30.
Article em En | MEDLINE | ID: mdl-32554494
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Cromatina / Doxorrubicina / Antineoplásicos Aspecto: Patient_preference Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Cromatina / Doxorrubicina / Antineoplásicos Aspecto: Patient_preference Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos