Your browser doesn't support javascript.
loading
Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.
Holden, Jeffrey K; Crawford, James J; Noland, Cameron L; Schmidt, Stephen; Zbieg, Jason R; Lacap, Jennifer A; Zang, Richard; Miller, Gregory M; Zhang, Yue; Beroza, Paul; Reja, Rohit; Lee, Wendy; Tom, Jeffrey Y K; Fong, Rina; Steffek, Micah; Clausen, Saundra; Hagenbeek, Thjis J; Hu, Taishan; Zhou, Zheng; Shen, Hong C; Cunningham, Christian N.
Afiliação
  • Holden JK; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA 94080, USA.
  • Crawford JJ; Department of Discovery Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Noland CL; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA.
  • Schmidt S; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA.
  • Zbieg JR; Department of Discovery Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Lacap JA; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Zang R; Department of Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA 94080, USA.
  • Miller GM; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA 94080, USA.
  • Zhang Y; Department of Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, USA.
  • Beroza P; Department of Discovery Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Reja R; Department of Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, USA.
  • Lee W; Department of Discovery Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Tom JYK; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA 94080, USA.
  • Fong R; Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA.
  • Steffek M; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA.
  • Clausen S; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA.
  • Hagenbeek TJ; Department of Discovery Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Hu T; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Shanghai 201203, People's Republic of China.
  • Zhou Z; Department of Lead Discovery, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Shanghai 201203, People's Republic of China.
  • Shen HC; Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Shanghai 201203, People's Republic of China.
  • Cunningham CN; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA 94080, USA. Electronic address: cunningham.christian@gene.com.
Cell Rep ; 31(12): 107809, 2020 06 23.
Article em En | MEDLINE | ID: mdl-32579935
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Transdução de Sinais / Proteínas Serina-Treonina Quinases / Bibliotecas de Moléculas Pequenas / Lipídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Transdução de Sinais / Proteínas Serina-Treonina Quinases / Bibliotecas de Moléculas Pequenas / Lipídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos