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The IMEx Coronavirus interactome: an evolving map of Coronaviridae-Host molecular interactions.
Perfetto, L; Pastrello, C; Del-Toro, N; Duesbury, M; Iannuccelli, M; Kotlyar, M; Licata, L; Meldal, B; Panneerselvam, K; Panni, S; Rahimzadeh, N; Ricard-Blum, S; Salwinski, L; Shrivastava, A; Cesareni, G; Pellegrini, M; Orchard, S; Jurisica, I; Hermjakob, H H; Porras, P.
Afiliação
  • Perfetto L; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.
  • Pastrello C; Krembil Research Institute, Data Science Discovery Centre for Chronic Diseases, University Health Network, 5KD-407, 60 Leonard Avenue, Toronto, ON, M5T 0S8, Canada.
  • Del-Toro N; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.
  • Duesbury M; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.
  • Iannuccelli M; UCLA-DOE Institute, UCLA, Los Angeles, USA.
  • Kotlyar M; Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, Rome, Italy.
  • Licata L; Krembil Research Institute, Data Science Discovery Centre for Chronic Diseases, University Health Network, 5KD-407, 60 Leonard Avenue, Toronto, ON, M5T 0S8, Canada.
  • Meldal B; Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, Rome, Italy.
  • Panneerselvam K; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.
  • Panni S; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.
  • Rahimzadeh N; Department of Biology, Ecology and Earth Sciences, Università della Calabria, Rende, Italy.
  • Ricard-Blum S; UCLA-DOE Institute, UCLA, Los Angeles, USA.
  • Salwinski L; Providence John Wayne Cancer Institute, Santa Monica, USA.
  • Shrivastava A; Univ Lyon, University Claude Bernard Lyon 1, INSA Lyon, CPE, Institute of Molecular and Supramolecular Chemistry and Biochemistry (ICBMS), UMR 5246, F-69622 Villeurbanne, France.
  • Cesareni G; UCLA-DOE Institute, UCLA, Los Angeles, USA.
  • Pellegrini M; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.
  • Orchard S; Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, Rome, Italy.
  • Jurisica I; Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, USA.
  • Hermjakob HH; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.
  • Porras P; Krembil Research Institute, Data Science Discovery Centre for Chronic Diseases, University Health Network, 5KD-407, 60 Leonard Avenue, Toronto, ON, M5T 0S8, Canada.
bioRxiv ; 2020 Jun 16.
Article em En | MEDLINE | ID: mdl-32587962
The current Coronavirus Disease 2019 (COVID-19) pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has spurred a wave of research of nearly unprecedented scale. Among the different strategies that are being used to understand the disease and develop effective treatments, the study of physical molecular interactions enables studying fine-grained resolution of the mechanisms behind the virus biology and the human organism response. Here we present a curated dataset of physical molecular interactions, manually extracted by IMEx Consortium curators focused on proteins from SARS-CoV-2, SARS-CoV-1 and other members of the Coronaviridae family. Currently, the dataset comprises over 2,200 binarized interactions extracted from 86 publications. The dataset can be accessed in the standard formats recommended by the Proteomics Standards Initiative (HUPO-PSI) at the IntAct database website ( www.ebi.ac.uk/intact ), and will be continuously updated as research on COVID-19 progresses.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: BioRxiv Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: BioRxiv Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos