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Bufalin inhibits hepatitis B virus-associated hepatocellular carcinoma development through androgen receptor dephosphorylation and cell cycle-related kinase degradation.
Yu, Zhuo; Feng, Hai; Zhuo, Yunhui; Li, Man; Zhu, Xiaojun; Huang, Lingying; Zhang, Xin; Zhou, Zhenhua; Zheng, Chao; Jiang, Yun; Le, Fan; Yu, Dae-Yeul; Cheng, Alfred Szelok; Sun, Xuehua; Gao, Yueqiu.
Afiliação
  • Yu Z; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China. zhuoyu@shutcm.edu.cn.
  • Feng H; Department of pharmacology, School of Pharmacy, Harbin Medical University, Harbin, People's Republic of China.
  • Zhuo Y; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China.
  • Li M; Laboratory of Cellular Immunity, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
  • Zhu X; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China.
  • Huang L; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China.
  • Zhang X; Laboratory of Cellular Immunity, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
  • Zhou Z; Laboratory of Cellular Immunity, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
  • Zheng C; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China.
  • Jiang Y; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China.
  • Le F; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China.
  • Yu DY; Disease Model Research Laboratory, Genome Editing Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-806, Republic of Korea.
  • Cheng AS; School of Biomedical Sciences, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, SAR, People's Republic of China.
  • Sun X; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China. susan_sxh@shutcm.edu.cn.
  • Gao Y; Liver Disease Department, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.528. Zhangheng Road, Pudong New District, Shanghai, People's Republic of China. gaoyueqiu@shutcm.edu.cn.
Cell Oncol (Dordr) ; 43(6): 1129-1145, 2020 Dec.
Article em En | MEDLINE | ID: mdl-32623699

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bufanolídeos / Receptores Androgênicos / Vírus da Hepatite B / Carcinoma Hepatocelular / Quinases Ciclina-Dependentes / Proteólise / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Cell Oncol (Dordr) Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bufanolídeos / Receptores Androgênicos / Vírus da Hepatite B / Carcinoma Hepatocelular / Quinases Ciclina-Dependentes / Proteólise / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Cell Oncol (Dordr) Ano de publicação: 2020 Tipo de documento: Article