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Late INa Blocker GS967 Supresses Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long QT Type 2.
Hwang, Jungmin; Kim, Tae Yun; Terentyev, Dmitry; Zhong, Mingwang; Kabakov, Anatoli Y; Bronk, Peter; Arunachalam, Karuppiah; Belardinelli, Luiz; Rajamani, Sridharan; Kunitomo, Yukiko; Pfeiffer, Zachary; Lu, Yichun; Peng, Xuwen; Odening, Katja E; Qu, Zhilin; Karma, Alain; Koren, Gideon; Choi, Bum-Rak.
Afiliação
  • Hwang J; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Kim TY; Department of Experiential Education, College of Pharmacy, University of Rhode Island, Kingstown (J.H.).
  • Terentyev D; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Zhong M; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Kabakov AY; Department of Physics, Northeastern University, Boston, MA (M.Z., A.K.).
  • Bronk P; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Arunachalam K; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Belardinelli L; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Rajamani S; Department of Biology, Gilead Science, Foster City, CA (L.B., S.R.).
  • Kunitomo Y; Department of Biology, Gilead Science, Foster City, CA (L.B., S.R.).
  • Pfeiffer Z; Amgen Inc, South San Francisco, CA (S.R.).
  • Lu Y; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Peng X; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Odening KE; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (J.H., T.Y.K., D.T., A.Y.K., P.B., K.A., Y.K., Z.P., Y.L., G.K., B.-R.C.).
  • Qu Z; Department of Comparative Medicine, Pennsylvania State University College of Medicine, Hershey (X.P.).
  • Karma A; Department of Cardiology & Angiology I, Heart Center, University of Freiburg, Germany (K.E.O.).
  • Koren G; Department of Medicine, University of California, Los Angeles (Z.Q.).
  • Choi BR; Department of Physics, Northeastern University, Boston, MA (M.Z., A.K.).
Circ Arrhythm Electrophysiol ; 13(8): e006875, 2020 08.
Article em En | MEDLINE | ID: mdl-32628505

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Síndrome do QT Longo / Canais de Sódio / Taquicardia Ventricular / Bloqueadores dos Canais de Sódio / Miócitos Cardíacos / Frequência Cardíaca / Antiarrítmicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Circ Arrhythm Electrophysiol Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Síndrome do QT Longo / Canais de Sódio / Taquicardia Ventricular / Bloqueadores dos Canais de Sódio / Miócitos Cardíacos / Frequência Cardíaca / Antiarrítmicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Circ Arrhythm Electrophysiol Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos