Pro-Inflammatory Signaling Upregulates a Neurotoxic Conotoxin-Like Protein Encrypted Within Human Endogenous Retrovirus-K.

Curzio, Domenico Di; Gurm, Mamneet; Turnbull, Matthew; Nadeau, Marie-Josée; Meek, Breanna; Rempel, Julia D; Fineblit, Samuel; Jonasson, Michael; Hebert, Sherry; Ferguson-Parry, Jennifer; Douville, Renée N

Curzio, Domenico Di; Gurm, Mamneet; Turnbull, Matthew; Nadeau, Marie-Josée; Meek, Breanna; Rempel, Julia D; Fineblit, Samuel; Jonasson, Michael; Hebert, Sherry; Ferguson-Parry, Jennifer; Douville, Renée N.

Afiliação

Curzio DD; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Gurm M; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Turnbull M; Department of Immunology, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB R3E 0T5, Canada.
Nadeau MJ; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Meek B; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Rempel JD; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Fineblit S; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Jonasson M; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Hebert S; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Ferguson-Parry J; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.
Douville RN; Department of Biology, University of Winnipeg, 599 Portage Avenue, Winnipeg, MB R3B 2G3, Canada.

Cells ; 9(7)2020 06 30.

Article em En | MEDLINE | ID: mdl-32629888

Assuntos

Esclerose Lateral Amiotrófica/metabolismo; Esclerose Lateral Amiotrófica/genética; Animais; Conotoxinas/genética; Conotoxinas/metabolismo; Retrovirus Endógenos/metabolismo; Retrovirus Endógenos/patogenicidade; Humanos; NF-kappa B/metabolismo; Necroptose/genética; Necroptose/fisiologia; Retroviridae/genética; Retroviridae/patogenicidade

Palavras-chave

HIV Tat; NF-κB; amyotrophic lateral sclerosis; conotoxin; endogenous retrovirus; myelination; necroptosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cells Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá País de publicação: Suíça

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