Evaluation of antifungal and disinfectant-resistant Candida species isolated from hospital wastewater.
Arch Microbiol
; 202(9): 2543-2550, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-32656678
ABSTRACT
The present study aims to examine the in vitro antifungal susceptibility patterns of Candida species isolated from hospital wastewater, and the efficacy of widely used disinfectants (sodium hypochlorite and benzalkonium chloride) against planktonic and biofilm cells were assessed. Susceptibility testing demonstrated that the two azoles were more effective against C. albicans than non-albicans isolates. When we determine the efficiency of disinfectants against the planktonic cells, benzalkonium chloride did not show any activity in all the studied strains under tested conditions except C. albicans-1. However, sodium hypochlorite showed ≥ 4 log10 killing in viable cells for different contact times. On the other hand, while 0.1% and 1% concentrations of benzalkonium chloride showed fungicidal activity against biofilm cells, sodium hypochlorite at 1% only demonstrated fungicidal activity. Those results showed that surface water is a possible transmission path for fungi in the investigated hospital region and may be a health risk, especially for the immunocompromised host.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Candida
/
Desinfetantes
/
Águas Residuárias
/
Antifúngicos
Idioma:
En
Revista:
Arch Microbiol
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Turquia