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Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses.
Brumpton, Ben; Sanderson, Eleanor; Heilbron, Karl; Hartwig, Fernando Pires; Harrison, Sean; Vie, Gunnhild Åberge; Cho, Yoonsu; Howe, Laura D; Hughes, Amanda; Boomsma, Dorret I; Havdahl, Alexandra; Hopper, John; Neale, Michael; Nivard, Michel G; Pedersen, Nancy L; Reynolds, Chandra A; Tucker-Drob, Elliot M; Grotzinger, Andrew; Howe, Laurence; Morris, Tim; Li, Shuai; Auton, Adam; Windmeijer, Frank; Chen, Wei-Min; Bjørngaard, Johan Håkon; Hveem, Kristian; Willer, Cristen; Evans, David M; Kaprio, Jaakko; Davey Smith, George; Åsvold, Bjørn Olav; Hemani, Gibran; Davies, Neil M.
Afiliação
  • Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway. ben.brumpton@ntnu.no.
  • Sanderson E; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK. ben.brumpton@ntnu.no.
  • Heilbron K; Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. ben.brumpton@ntnu.no.
  • Hartwig FP; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Harrison S; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, BS8 2BN, UK.
  • Vie GÅ; 23andMe, Inc., 223 N Mathilda Avenue, Sunnyvale, CA, 94086, USA.
  • Cho Y; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Howe LD; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
  • Hughes A; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Boomsma DI; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, BS8 2BN, UK.
  • Havdahl A; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
  • Hopper J; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Neale M; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, BS8 2BN, UK.
  • Nivard MG; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Pedersen NL; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, BS8 2BN, UK.
  • Reynolds CA; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Tucker-Drob EM; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, BS8 2BN, UK.
  • Grotzinger A; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Howe L; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Morris T; Nic Waals Institute, Lovisenberg Diaconal Hospital, Spångbergveien 25, 0853, Oslo, Norway.
  • Li S; Department of Mental Disorders, Norwegian Institute of Public Health, Sandakerveien 24 C, 0473, Oslo, Norway.
  • Auton A; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Windmeijer F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Chen WM; Department of Psychology, University of California Riverside, Riverside, CA, USA.
  • Bjørngaard JH; Department of Psychology and Population Research Center, University of Texas at Austin, 108 E. Dean Keeton Stop A8000,, Austin, TX, 78712, USA.
  • Hveem K; Department of Psychology and Population Research Center, University of Texas at Austin, 108 E. Dean Keeton Stop A8000,, Austin, TX, 78712, USA.
  • Willer C; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Evans DM; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, BS8 2BN, UK.
  • Kaprio J; Medical Research Council Integrative Epidemiology Unit, University of Bristol, BS8 2BN, Bristol, UK.
  • Davey Smith G; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol, BS8 2BN, UK.
  • Åsvold BO; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207 Bouverie Street, Carlton, VIC, 3053, Australia.
  • Hemani G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, CB1 8RN, UK.
Nat Commun ; 11(1): 3519, 2020 07 14.
Article em En | MEDLINE | ID: mdl-32665587
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Noruega País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Noruega País de publicação: Reino Unido