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Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Thoms, Matthias; Buschauer, Robert; Ameismeier, Michael; Koepke, Lennart; Denk, Timo; Hirschenberger, Maximilian; Kratzat, Hanna; Hayn, Manuel; Mackens-Kiani, Timur; Cheng, Jingdong; Straub, Jan H; Stürzel, Christina M; Fröhlich, Thomas; Berninghausen, Otto; Becker, Thomas; Kirchhoff, Frank; Sparrer, Konstantin M J; Beckmann, Roland.
Afiliação
  • Thoms M; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Buschauer R; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Ameismeier M; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Koepke L; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Denk T; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Hirschenberger M; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Kratzat H; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Hayn M; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Mackens-Kiani T; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Cheng J; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Straub JH; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Stürzel CM; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Fröhlich T; Laboratory of Functional Genome Analysis, University of Munich, Munich, Germany.
  • Berninghausen O; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Becker T; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany.
  • Kirchhoff F; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
  • Sparrer KMJ; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany. beckmann@genzentrum.lmu.de konstantin.sparrer@uni-ulm.de.
  • Beckmann R; Gene Center Munich, Department of Biochemistry, University of Munich, Munich, Germany. beckmann@genzentrum.lmu.de konstantin.sparrer@uni-ulm.de.
Science ; 369(6508): 1249-1255, 2020 09 04.
Article em En | MEDLINE | ID: mdl-32680882

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Proteínas não Estruturais Virais / Evasão da Resposta Imune / Betacoronavirus / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Proteínas não Estruturais Virais / Evasão da Resposta Imune / Betacoronavirus / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos