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TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction.
Madan, Aditi; Viswanathan, Meera C; Woulfe, Kathleen C; Schmidt, William; Sidor, Agnes; Liu, Ting; Nguyen, Tran H; Trinh, Bosco; Wilson, Cortney; Madathil, Sineej; Vogler, Georg; O'Rourke, Brian; Biesiadecki, Brandon J; Tobacman, Larry S; Cammarato, Anthony.
Afiliação
  • Madan A; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205.
  • Viswanathan MC; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205.
  • Woulfe KC; Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO 80045.
  • Schmidt W; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205.
  • Sidor A; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205.
  • Liu T; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205.
  • Nguyen TH; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205.
  • Trinh B; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037.
  • Wilson C; Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO 80045.
  • Madathil S; Department of Medicine, University of Illinois College of Medicine, Chicago, IL 60612.
  • Vogler G; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037.
  • O'Rourke B; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205.
  • Biesiadecki BJ; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH 43210.
  • Tobacman LS; The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210.
  • Cammarato A; Department of Medicine, University of Illinois College of Medicine, Chicago, IL 60612.
Proc Natl Acad Sci U S A ; 117(31): 18822-18831, 2020 08 04.
Article em En | MEDLINE | ID: mdl-32690703
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tropomiosina / Troponina T / Mutação / Cardiomiopatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tropomiosina / Troponina T / Mutação / Cardiomiopatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos