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(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A.
Michalak, Malwina; Katzenmaier, Eva-Maria; Roeckel, Nina; Woerner, Stefan M; Fuchs, Vera; Warnken, Uwe; Yuan, Yan P; Bork, Peer; Neu-Yilik, Gabriele; Kulozik, Andreas; von Knebel Doeberitz, Magnus; Kloor, Matthias; Kopitz, Jürgen; Gebert, Johannes.
Afiliação
  • Michalak M; Department of Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
  • Katzenmaier EM; Molecular Medicine Partnership Unit, Medical Faculty of the University of Heidelberg and European Molecular Biology Laboratory, 69120 Heidelberg, Germany.
  • Roeckel N; Department of Pediatric Oncology, Hematology and Immunology, Children's Hospital, University of Heidelberg, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.
  • Woerner SM; Department of Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
  • Fuchs V; Molecular Medicine Partnership Unit, Medical Faculty of the University of Heidelberg and European Molecular Biology Laboratory, 69120 Heidelberg, Germany.
  • Warnken U; Department of Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
  • Yuan YP; Molecular Medicine Partnership Unit, Medical Faculty of the University of Heidelberg and European Molecular Biology Laboratory, 69120 Heidelberg, Germany.
  • Bork P; Department of Internal Medicine I, Endocrinology and Metabolism, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
  • Neu-Yilik G; Department of Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
  • Kulozik A; Molecular Medicine Partnership Unit, Medical Faculty of the University of Heidelberg and European Molecular Biology Laboratory, 69120 Heidelberg, Germany.
  • von Knebel Doeberitz M; Clinical Cooperation Unit Neurooncology, DKFZ (German Cancer Research Center), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Kloor M; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstraße 1, 69117 Heidelberg, Germany.
  • Kopitz J; Molecular Medicine Partnership Unit, Medical Faculty of the University of Heidelberg and European Molecular Biology Laboratory, 69120 Heidelberg, Germany.
  • Gebert J; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstraße 1, 69117 Heidelberg, Germany.
Int J Mol Sci ; 21(15)2020 Jul 23.
Article em En | MEDLINE | ID: mdl-32718059
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Neoplasias Colorretais / Mutação da Fase de Leitura / Proteínas de Ligação a RNA / Repetições de Microssatélites / Instabilidade Genômica / Degradação do RNAm Mediada por Códon sem Sentido / Proteínas de Neoplasias Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Neoplasias Colorretais / Mutação da Fase de Leitura / Proteínas de Ligação a RNA / Repetições de Microssatélites / Instabilidade Genômica / Degradação do RNAm Mediada por Códon sem Sentido / Proteínas de Neoplasias Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Suíça