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Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening.
Otsuka, Yuka; Airola, Michael V; Choi, Yong-Mi; Coant, Nicolas; Snider, Justin; Cariello, Chris; Saied, Essa M; Arenz, Christoph; Bannister, Thomas; Rahaim, Ron; Hannun, Yusuf A; Shumate, Justin; Scampavia, Louis; Haley, John D; Spicer, Timothy P.
Afiliação
  • Otsuka Y; Department of Molecular Medicine, Scripps Research, The Scripps Research Molecular Screening Center, Jupiter, FL, USA.
  • Airola MV; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
  • Choi YM; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
  • Coant N; Stony Brook University Cancer Center, Stony Brook, NY, USA.
  • Snider J; Stony Brook University Cancer Center, Stony Brook, NY, USA.
  • Cariello C; Department of Pathology, Stony Brook Renaissance School of Medicine, Stony Brook, NY, USA.
  • Saied EM; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt.
  • Arenz C; Institute for Chemistry, Humboldt Universität zu Berlin, Berlin, Germany.
  • Bannister T; Department of Molecular Medicine, Scripps Research, The Scripps Research Molecular Screening Center, Jupiter, FL, USA.
  • Rahaim R; Department of Molecular Medicine, Scripps Research, The Scripps Research Molecular Screening Center, Jupiter, FL, USA.
  • Hannun YA; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
  • Shumate J; Stony Brook University Cancer Center, Stony Brook, NY, USA.
  • Scampavia L; Department of Molecular Medicine, Scripps Research, The Scripps Research Molecular Screening Center, Jupiter, FL, USA.
  • Haley JD; Department of Molecular Medicine, Scripps Research, The Scripps Research Molecular Screening Center, Jupiter, FL, USA.
  • Spicer TP; Stony Brook University Cancer Center, Stony Brook, NY, USA.
SLAS Discov ; 26(1): 113-121, 2021 01.
Article em En | MEDLINE | ID: mdl-32734807
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Ceramidase Neutra / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: SLAS Discov Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Ceramidase Neutra / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: SLAS Discov Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos