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Generation of Leads for γ-Secretase Modulation.
Mandal, Mihirbaran; Buevich, Alexei; Caldwell, John P; Hyde, Lynn; Huang, Xianhai; Liu, Xiaoxiang; McKittrick, Brian; Mazzola, Robert D; Pissarnitski, Dmitri; Palani, Anandan; Zhang, Lili; Parker, Eric; Xiao, Li; Rindgen, Diane; Zhu, Zhaoning.
Afiliação
  • Mandal M; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Buevich A; Department of NMR Structure Elucidation, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Caldwell JP; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Hyde L; Department of Neuroscience, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Huang X; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Liu X; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • McKittrick B; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Mazzola RD; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Pissarnitski D; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Palani A; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Zhang L; Department of Neuroscience, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Parker E; Department of Neuroscience, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Xiao L; Department of Modeling and Informatics, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Rindgen D; Department of Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Zhu Z; Department of Medicinal Chemistry, Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
J Med Chem ; 63(15): 8216-8230, 2020 08 13.
Article em En | MEDLINE | ID: mdl-32786237

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Secretases da Proteína Precursora do Amiloide Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Secretases da Proteína Precursora do Amiloide Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos