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Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits.
Glastonbury, Craig A; Pulit, Sara L; Honecker, Julius; Censin, Jenny C; Laber, Samantha; Yaghootkar, Hanieh; Rahmioglu, Nilufer; Pastel, Emilie; Kos, Katerina; Pitt, Andrew; Hudson, Michelle; Nellåker, Christoffer; Beer, Nicola L; Hauner, Hans; Becker, Christian M; Zondervan, Krina T; Frayling, Timothy M; Claussnitzer, Melina; Lindgren, Cecilia M.
Afiliação
  • Glastonbury CA; Big Data Institute, University of Oxford, Oxford, United Kingdom.
  • Pulit SL; BenevolentAI, London, United Kingdom.
  • Honecker J; Big Data Institute, University of Oxford, Oxford, United Kingdom.
  • Censin JC; Else Kröner-Fresenius-Center for Nutritional Medicine, School of Life Sciences, Technical University of Munich, Freising, Germany.
  • Laber S; Big Data Institute, University of Oxford, Oxford, United Kingdom.
  • Yaghootkar H; Wellcome Centre for Human Genetics (WCHG), Oxford, United Kingdom.
  • Rahmioglu N; Big Data Institute, University of Oxford, Oxford, United Kingdom.
  • Pastel E; Broad Institute of MIT and Harvard, Cambridge Massachusetts, United States of America.
  • Kos K; Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, United Kingdom.
  • Pitt A; Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, United Kingdom.
  • Hudson M; Wellcome Centre for Human Genetics (WCHG), Oxford, United Kingdom.
  • Nellåker C; Endometriosis CaRe Centre Oxford, Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom.
  • Beer NL; Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, United Kingdom.
  • Hauner H; Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, United Kingdom.
  • Becker CM; NIHR Exeter Clinical Research Facility, University of Exeter Medical School, University of Exeter and Royal Devon and Exeter NHS Foundation Trust Exeter, United Kingdom.
  • Zondervan KT; NIHR Exeter Clinical Research Facility, University of Exeter Medical School, University of Exeter and Royal Devon and Exeter NHS Foundation Trust Exeter, United Kingdom.
  • Frayling TM; Big Data Institute, University of Oxford, Oxford, United Kingdom.
  • Claussnitzer M; Endometriosis CaRe Centre Oxford, Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom.
  • Lindgren CM; Novo Nordisk Research Centre Oxford (NNRCO), Oxford, United Kingdom.
PLoS Comput Biol ; 16(8): e1008044, 2020 08.
Article em En | MEDLINE | ID: mdl-32797044

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adipócitos / Aprendizado de Máquina / Obesidade Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adipócitos / Aprendizado de Máquina / Obesidade Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos