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Age-induced accumulation of methylmalonic acid promotes tumour progression.
Gomes, Ana P; Ilter, Didem; Low, Vivien; Endress, Jennifer E; Fernández-García, Juan; Rosenzweig, Adam; Schild, Tanya; Broekaert, Dorien; Ahmed, Adnan; Planque, Melanie; Elia, Ilaria; Han, Julie; Kinzig, Charles; Mullarky, Edouard; Mutvei, Anders P; Asara, John; de Cabo, Rafael; Cantley, Lewis C; Dephoure, Noah; Fendt, Sarah-Maria; Blenis, John.
Afiliação
  • Gomes AP; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. ana.gomes@moffitt.org.
  • Ilter D; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA. ana.gomes@moffitt.org.
  • Low V; Department of Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA. ana.gomes@moffitt.org.
  • Endress JE; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Fernández-García J; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
  • Rosenzweig A; Department of Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA.
  • Schild T; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Broekaert D; The Biochemistry, Structural, Developmental, Cell and Molecular Biology Allied PhD Program, Weill Cornell Medicine, New York, NY, USA.
  • Ahmed A; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Planque M; The Biochemistry, Structural, Developmental, Cell and Molecular Biology Allied PhD Program, Weill Cornell Medicine, New York, NY, USA.
  • Elia I; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.
  • Han J; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
  • Kinzig C; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Mullarky E; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
  • Mutvei AP; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Asara J; The Biochemistry, Structural, Developmental, Cell and Molecular Biology Allied PhD Program, Weill Cornell Medicine, New York, NY, USA.
  • de Cabo R; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.
  • Cantley LC; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
  • Dephoure N; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Fendt SM; Department of Biochemistry, Weill Cornell Medicine, New York, NY, USA.
  • Blenis J; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.
Nature ; 585(7824): 283-287, 2020 09.
Article em En | MEDLINE | ID: mdl-32814897
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Progressão da Doença / Ácido Metilmalônico / Invasividade Neoplásica / Metástase Neoplásica / Neoplasias Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Progressão da Doença / Ácido Metilmalônico / Invasividade Neoplásica / Metástase Neoplásica / Neoplasias Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido