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GOLPH3 inhibition reverses oxaliplatin resistance of colon cancer cells via suppression of PI3K/AKT/mTOR pathway.
Yu, Tao; An, Qi; Cao, Xiang-Long; Yang, Hua; Cui, Jian; Li, Zi-Jian; Xiao, Gang.
Afiliação
  • Yu T; Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, PR China.
  • An Q; Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, PR China.
  • Cao XL; Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, PR China.
  • Yang H; Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, PR China.
  • Cui J; Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, PR China.
  • Li ZJ; Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, PR China.
  • Xiao G; Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, PR China. Electronic address: xgbj@sina.com.
Life Sci ; 260: 118294, 2020 Nov 01.
Article em En | MEDLINE | ID: mdl-32818544
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Oxaliplatina / Proteínas de Membrana Tipo de estudo: Clinical_trials Limite: Animals / Humans / Male Idioma: En Revista: Life Sci Ano de publicação: 2020 Tipo de documento: Article País de publicação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Oxaliplatina / Proteínas de Membrana Tipo de estudo: Clinical_trials Limite: Animals / Humans / Male Idioma: En Revista: Life Sci Ano de publicação: 2020 Tipo de documento: Article País de publicação: Holanda