HMGB1 Inhibits HNF1A to Modulate Liver Fibrogenesis via p65/miR-146b Signaling.

Ge, Shanfei; Wu, Xiaoping; Xiong, Ying; Xie, Jianping; Liu, Fei; Zhang, Wenfeng; Yang, Lixia; Zhang, Song; Lai, Lingling; Huang, Jiansheng; Li, Ming; Yu, Yan-Qing

Ge, Shanfei; Wu, Xiaoping; Xiong, Ying; Xie, Jianping; Liu, Fei; Zhang, Wenfeng; Yang, Lixia; Zhang, Song; Lai, Lingling; Huang, Jiansheng; Li, Ming; Yu, Yan-Qing.

Afiliação

Ge S; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Wu X; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Xiong Y; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Xie J; Department of Infectious Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Liu F; Department of Infectious Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhang W; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Yang L; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Zhang S; Department of Infectious Disease, ShangRao People's Hospital, ShangRao, Jiangxi, China.
Lai L; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Huang J; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Li M; Department of Infectious Disease, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Yu YQ; Department of Pathology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.

DNA Cell Biol ; 39(9): 1711-1722, 2020 Sep.

Article em En | MEDLINE | ID: mdl-32833553

Assuntos

Proteína HMGB1/metabolismo; Fator 1-alfa Nuclear de Hepatócito/metabolismo; Cirrose Hepática/metabolismo; Transdução de Sinais; Regiões 3' não Traduzidas; Animais; Linhagem Celular; Proteína HMGB1/genética; Células Estreladas do Fígado/metabolismo; Fator 1-alfa Nuclear de Hepatócito/genética; MicroRNAs/genética; MicroRNAs/metabolismo; Ratos; Ratos Sprague-Dawley; Fator de Transcrição RelA/genética; Fator de Transcrição RelA/metabolismo

Palavras-chave

HMGB1; HNF1A; hepatic stellate cells (HSCs); liver fibrosis; miR-146b

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteína HMGB1 / Fator 1-alfa Nuclear de Hepatócito / Cirrose Hepática Limite: Animals Idioma: En Revista: DNA Cell Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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