Functional respiratory imaging identifies redistribution of pulmonary blood flow in patients with COVID-19.
Thorax
; 76(2): 182-184, 2021 02.
Article
em En
| MEDLINE
| ID: mdl-32859733
ABSTRACT
An increasing observation is that some patients with COVID-19 have normal lung compliance but significant hypoxaemia different from typical acute respiratory distress syndrome (ARDS). We hypothesised that changes in pulmonary blood distribution may be partially responsible and used functional respiratory imaging on CT scans to calculate pulmonary blood volume. We found that patients with COVID-19 had significantly reduced blood volume in the smaller calibre blood vessels (here defined as <5 mm2 cross-sectional area) compared with matched ARDS patients and healthy controls. This suggests that using high levels of PEEP may not alone be enough to oxygenate these patients and that additional management strategies may be needed.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mecânica Respiratória
/
Complacência Pulmonar
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Circulação Pulmonar
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SARS-CoV-2
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COVID-19
/
Pulmão
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Thorax
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Reino Unido