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Sarsasapogenin alleviates diabetic nephropathy through suppression of chronic inflammation by down-regulating PAR-1: In vivo and in vitro study.
Tang, Zhuang-Zhuang; Zhang, Yu-Meng; Zheng, Ting; Huang, Ting-Ting; Ma, Teng-Fei; Liu, Yao-Wu.
Afiliação
  • Tang ZZ; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Zhang YM; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Zheng T; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Huang TT; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Ma TF; Institute for Stem Cell and Neural Regeneration; Key Laboratory of Cardiovascular & Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Liu YW; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China; Department of Pharmacology, School of Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China. Electronic address: ywliu@xzhmu.edu.cn.
Phytomedicine ; 78: 153314, 2020 Nov.
Article em En | MEDLINE | ID: mdl-32882582
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espirostanos / Receptor PAR-1 / Nefropatias Diabéticas / Células Mesangiais Limite: Animals / Humans / Male Idioma: En Revista: Phytomedicine Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Alemanha
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espirostanos / Receptor PAR-1 / Nefropatias Diabéticas / Células Mesangiais Limite: Animals / Humans / Male Idioma: En Revista: Phytomedicine Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Alemanha