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Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer.
Wang, Rong; Yamada, Tadaaki; Kita, Kenji; Taniguchi, Hirokazu; Arai, Sachiko; Fukuda, Koji; Terashima, Minoru; Ishimura, Akihiko; Nishiyama, Akihiro; Tanimoto, Azusa; Takeuchi, Shinji; Ohtsubo, Koshiro; Yamashita, Kaname; Yamano, Tomoyoshi; Yoshimura, Akihiro; Takayama, Koichi; Kaira, Kyoichi; Taniguchi, Yoshihiko; Atagi, Shinji; Uehara, Hisanori; Hanayama, Rikinari; Matsumoto, Isao; Han, Xujun; Matsumoto, Kunio; Wang, Wei; Suzuki, Takeshi; Yano, Seiji.
Afiliação
  • Wang R; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Yamada T; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Kita K; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan. tayamada@koto.kpu-m.ac.jp.
  • Taniguchi H; Department of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan. tayamada@koto.kpu-m.ac.jp.
  • Arai S; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Fukuda K; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Terashima M; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
  • Ishimura A; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Nishiyama A; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Tanimoto A; Nano Life Science Institute, Kanazawa University, Kanazawa, Japan.
  • Takeuchi S; Division of Functional Genomics, Cancer Research Institute, Kanazawa University Kanazawa, Kanazawa, Japan.
  • Ohtsubo K; Division of Functional Genomics, Cancer Research Institute, Kanazawa University Kanazawa, Kanazawa, Japan.
  • Yamashita K; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Yamano T; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Yoshimura A; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Takayama K; Nano Life Science Institute, Kanazawa University, Kanazawa, Japan.
  • Kaira K; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Taniguchi Y; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
  • Atagi S; Department of Immunology, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan.
  • Uehara H; Department of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Hanayama R; Department of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Matsumoto I; Department of Respiratory Medicine, Comprehensive Cancer Center, International Medical Center, Saitama Medical University, Hidaka, Japan.
  • Han X; Department of Thoracic Oncology, National Hospital Organization Kinki-chuo Chest Medical Center, Sakai, Japan.
  • Matsumoto K; Department of Thoracic Oncology, National Hospital Organization Kinki-chuo Chest Medical Center, Sakai, Japan.
  • Wang W; Division of Pathology, Tokushima University Hospital, Tokushima, Japan.
  • Suzuki T; Nano Life Science Institute, Kanazawa University, Kanazawa, Japan.
  • Yano S; Department of Immunology, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan.
Nat Commun ; 11(1): 4607, 2020 09 14.
Article em En | MEDLINE | ID: mdl-32929081
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acrilamidas / Proteínas Proto-Oncogênicas / Receptor IGF Tipo 1 / Receptores Proteína Tirosina Quinases / Compostos de Anilina / Neoplasias Pulmonares / Mutação Tipo de estudo: Prognostic_studies Limite: Aged80 / Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acrilamidas / Proteínas Proto-Oncogênicas / Receptor IGF Tipo 1 / Receptores Proteína Tirosina Quinases / Compostos de Anilina / Neoplasias Pulmonares / Mutação Tipo de estudo: Prognostic_studies Limite: Aged80 / Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido