Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evolution.

Vangenot, Christelle; Nunes, José Manuel; Doxiadis, Gaby M; Poloni, Estella S; Bontrop, Ronald E; de Groot, Natasja G; Sanchez-Mazas, Alicia

Vangenot, Christelle; Nunes, José Manuel; Doxiadis, Gaby M; Poloni, Estella S; Bontrop, Ronald E; de Groot, Natasja G; Sanchez-Mazas, Alicia.

Afiliação

Vangenot C; Laboratory of Anthropology, Genetics and Peopling History, Department of Genetics and Evolution, Anthropology Unit, University of Geneva, Geneva, Switzerland.
Nunes JM; Laboratory of Anthropology, Genetics and Peopling History, Department of Genetics and Evolution, Anthropology Unit, University of Geneva, Geneva, Switzerland.
Doxiadis GM; Institute of Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.
Poloni ES; Comparative Genetics and Refinement, Biomedical Primate Research Centre, 2288, GJ, Rijswijk, The Netherlands.
Bontrop RE; Laboratory of Anthropology, Genetics and Peopling History, Department of Genetics and Evolution, Anthropology Unit, University of Geneva, Geneva, Switzerland.
de Groot NG; Institute of Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.
Sanchez-Mazas A; Comparative Genetics and Refinement, Biomedical Primate Research Centre, 2288, GJ, Rijswijk, The Netherlands.

BMC Evol Biol ; 20(1): 119, 2020 09 15.

Article em En | MEDLINE | ID: mdl-32933484

Assuntos

Evolução Molecular; Variação Genética; Antígenos HLA-D/genética; Hominidae/genética; Desequilíbrio de Ligação; Pan troglodytes; Alelos; Animais; Frequência do Gene; Genética Populacional; Haplótipos; Humanos; Pan troglodytes/genética

Palavras-chave

Balancing selection; Demographic history; HLA; Human populations; Linkage disequilibrium; MHC; Nucleotide diversity; Patr; Population bottleneck; Selective sweep; Western chimpanzees

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Hominidae / Antígenos HLA-D / Desequilíbrio de Ligação / Pan troglodytes / Evolução Molecular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: BMC Evol Biol Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido

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