Toxicities of Neonicotinoid-Containing Pesticide Mixtures on Nontarget Organisms.
Environ Toxicol Chem
; 39(10): 1884-1893, 2020 10.
Article
em En
| MEDLINE
| ID: mdl-32936472
ABSTRACT
Neonicotinoids are a widely used class of pesticides. Co-exposure to neonicotinoids and other classes of pesticides can exert potentiating or synergistic effects, and these mixtures have been detected in human bodily fluids. The present review summarizes studies into the effects of neonicotinoid-containing pesticide mixtures on humans and other nontarget organisms. Exposure to these mixtures has been reported to result in reproductive and hormonal toxicity, genotoxicity, neurotoxicity, hepatotoxicity, and immunotoxicity in vertebrates. Mortality of pollinators and toxicity in other organisms has also been reported. The underlying mechanism of pesticide mixture toxicity may be associated with impairment of cytochrome 450 enzymes, which are involved in metabolizing pesticides. However, a comprehensive explanation of the adverse effects of neonicotinoid-containing pesticide mixtures is still required so that effective prevention and control measures can be formulated. Environ Toxicol Chem 2020;391884-1893. © 2020 SETAC.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Praguicidas
/
Exposição Ambiental
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Neonicotinoides
Limite:
Animals
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Humans
Idioma:
En
Revista:
Environ Toxicol Chem
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China