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A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Daou, Salima; Talukdar, Manisha; Tang, Jinle; Dong, Beihua; Banerjee, Shuvojit; Li, Yize; Duffy, Nicole M; Ogunjimi, Abiodun A; Gaughan, Christina; Jha, Babal K; Gish, Gerald; Tavernier, Nicolas; Mao, Daniel; Weiss, Susan R; Huang, Hao; Silverman, Robert H; Sicheri, Frank.
Afiliação
  • Daou S; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Talukdar M; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada.
  • Tang J; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Dong B; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada.
  • Banerjee S; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Li Y; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Duffy NM; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Ogunjimi AA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Gaughan C; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada.
  • Jha BK; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada.
  • Gish G; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Tavernier N; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Mao D; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada.
  • Weiss SR; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada.
  • Huang H; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Silverman RH; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, Canada.
  • Sicheri F; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Proc Natl Acad Sci U S A ; 117(40): 24802-24812, 2020 10 06.
Article em En | MEDLINE | ID: mdl-32958664
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenosina Desaminase / Fenol / Doenças Autoimunes do Sistema Nervoso / Endorribonucleases / Inibidores Enzimáticos / Malformações do Sistema Nervoso Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenosina Desaminase / Fenol / Doenças Autoimunes do Sistema Nervoso / Endorribonucleases / Inibidores Enzimáticos / Malformações do Sistema Nervoso Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá País de publicação: Estados Unidos