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Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture.
Zhang, Qian; Sidorenko, Julia; Couvy-Duchesne, Baptiste; Marioni, Riccardo E; Wright, Margaret J; Goate, Alison M; Marcora, Edoardo; Huang, Kuan-Lin; Porter, Tenielle; Laws, Simon M; Sachdev, Perminder S; Mather, Karen A; Armstrong, Nicola J; Thalamuthu, Anbupalam; Brodaty, Henry; Yengo, Loic; Yang, Jian; Wray, Naomi R; McRae, Allan F; Visscher, Peter M.
Afiliação
  • Zhang Q; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.
  • Sidorenko J; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.
  • Couvy-Duchesne B; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.
  • Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.
  • Wright MJ; Queensland Brain Institute, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Goate AM; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Marcora E; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Huang KL; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Porter T; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Laws SM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Sachdev PS; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Mather KA; Collaborative Genomics Group, Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Armstrong NJ; Collaborative Genomics Group, Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Thalamuthu A; School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia.
  • Yengo L; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.
  • Yang J; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia.
  • Wray NR; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.
  • McRae AF; Neuroscience Research Australia, Sydney, NSW, Australia.
  • Visscher PM; Department of Mathematics and Statistics, Murdoch University, Perth, WA, Australia.
Nat Commun ; 11(1): 4799, 2020 09 23.
Article em En | MEDLINE | ID: mdl-32968074

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Predisposição Genética para Doença / Estudos de Associação Genética / Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Predisposição Genética para Doença / Estudos de Associação Genética / Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália País de publicação: Reino Unido