Risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus: A clinical study.
Pak J Med Sci
; 36(6): 1344-1348, 2020.
Article
em En
| MEDLINE
| ID: mdl-32968406
ABSTRACT
OBJECTIVES:
To determine risk factors for peripheral arterial disease (PAD) in elderly patients with Type-2 diabetes mellitus.METHODS:
The elderly patients with Type-2 diabetes treated in the Central Hospital of Cangzhou were enrolled and divided into PAD group and non-PAD group between October 2016 and November 2019, The data of the patients including age, gender, body mass index, blood pressure, hemoglobin A1c, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, total cholesterol, triglyceride, white cell count, lymphocyte count, high-sensitivity C-reactive protein, uric acid as well as living habits and complications of Type-2 diabetes mellitus were recorded to determine the risk factors for PAD.RESULTS:
One thousand four hundred seventy six (1476) patients were enrolled, in which 465 patients were included in group of PAD, and 1011 in non-PAD group. The univariate analysis revealed that the two groups significantly differed in age (p=0.003), course of T2DM (p=0.001), hypertension (p=0.006), smoking habits (p<0.001), hyperuricemia (p<0.01), high-sensitivity C-reactive protein (p<0.01), white cell count (p<0.001), lymphocyte count (p<0.001) and diabetic neuropathy (p<0.001). In the multivariate analysis, age (OR 1.56, 95% CI 1.21-1.89), smoking habit (OR 1.37, 95% CI 1.19-1.68), hypertension (OR 1.44, 95% CI 1.15-1.98), diabetic neuropathy (OR 3.55, 95% CI 2.14-4.29), high-sensitivity C-reactive protein (OR 1.74, 95% CI 1.39-2.61) and hyperuricemia (OR 2.71, 95% CI 1.66-3.87) were significant risk factors for PAD.CONCLUSIONS:
Age, smoking habit, hypertension, diabetic neuropathy, high-sensitivity C-reactive protein and hyperuricemia were independent risk factors for peripheral arterial disease in elderly patients with Type-2 diabetes mellitus.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Pak J Med Sci
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China