FBXW5 acts as a negative regulator of pathological cardiac hypertrophy by decreasing the TAK1 signaling to pro-hypertrophic members of the MAPK signaling pathway.

Hui, Xuejun; Hu, Fengjiao; Liu, Jia; Li, Changhai; Yang, Yang; Shu, Shangzhi; Liu, Peipei; Wang, Fan; Li, Shuyan

Hui, Xuejun; Hu, Fengjiao; Liu, Jia; Li, Changhai; Yang, Yang; Shu, Shangzhi; Liu, Peipei; Wang, Fan; Li, Shuyan.

Afiliação

Hui X; Jilin University, Changchun, Jilin, China; Second Hospital of Jilin University, Department of Cardiology the Medical Science Research Center, China.
Hu F; Medical Science Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Liu J; Department of Cardiology, Cang Zhou People's Hospital, Cangzhou, Hebei, China.
Li C; Jilin University, Changchun, Jilin, China; Department of Cardiology, First Hospital of Jilin University, Changchun, Jilin, China.
Yang Y; Jilin University, Changchun, Jilin, China; Department of Cardiology, First Hospital of Jilin University, Changchun, Jilin, China.
Shu S; Jilin University, Changchun, Jilin, China; Department of Cardiology, First Hospital of Jilin University, Changchun, Jilin, China.
Liu P; Department of Cardiology, Cang Zhou People's Hospital, Cangzhou, Hebei, China.
Wang F; Jilin University, Changchun, Jilin, China; Department of Cardiology, First Hospital of Jilin University, Changchun, Jilin, China.
Li S; Jilin University, Changchun, Jilin, China; Department of Cardiology, First Hospital of Jilin University, Changchun, Jilin, China. Electronic address: shuyanli1992@163.com.

J Mol Cell Cardiol ; 151: 31-43, 2021 02.

Article em En | MEDLINE | ID: mdl-32971071

Assuntos

Cardiomegalia/metabolismo; Cardiomegalia/patologia; Proteínas F-Box/metabolismo; MAP Quinase Quinase Quinases/metabolismo; Sistema de Sinalização das MAP Quinases; Animais; Animais Recém-Nascidos; Dependovirus/metabolismo; Regulação para Baixo; Fibrose; Humanos; Proteínas Quinases JNK Ativadas por Mitógeno/metabolismo; Camundongos Knockout; Poliubiquitina/metabolismo; Ligação Proteica; Ratos; Ubiquitinação; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

Cardiac hypertrophy; FBXW5; MAPK; TAK1

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomegalia / MAP Quinase Quinase Quinases / Sistema de Sinalização das MAP Quinases / Proteínas F-Box Limite: Animals / Humans Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google