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Dicoumarol, an NQO1 inhibitor, blocks cccDNA transcription by promoting degradation of HBx.
Cheng, Sheng-Tao; Hu, Jie-Li; Ren, Ji-Hua; Yu, Hai-Bo; Zhong, Shan; Wai Wong, Vincent Kam; Kwan Law, Betty Yuen; Chen, Wei-Xian; Xu, Hong-Mei; Zhang, Zhen-Zhen; Cai, Xue-Fei; Hu, Yuan; Zhang, Wen-Lu; Long, Quan-Xin; Ren, Fang; Zhou, Hong-Zhong; Huang, Ai-Long; Chen, Juan.
Afiliação
  • Cheng ST; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Hu JL; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Ren JH; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Yu HB; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Zhong S; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Wai Wong VK; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Kwan Law BY; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Chen WX; Department of Clinical Laboratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Xu HM; Department of Infectious Diseases, The Children's Hospital of Chongqing Medical University, Chongqing, China.
  • Zhang ZZ; Department of Infectious Diseases, The Children's Hospital of Chongqing Medical University, Chongqing, China.
  • Cai XF; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Hu Y; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Zhang WL; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Long QX; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Ren F; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Zhou HZ; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Huang AL; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. Electronic address: ahuang1964@163.com.
  • Chen J; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. Electronic address: chenjuan2014@cqmu.edu.cn.
J Hepatol ; 74(3): 522-534, 2021 03.
Article em En | MEDLINE | ID: mdl-32987030
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Transcrição Gênica / Dicumarol / DNA Circular / Transativadores / Vírus da Hepatite B / NAD(P)H Desidrogenase (Quinona) / Hepatite B Crônica / Proteínas Virais Reguladoras e Acessórias / Proteólise Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Transcrição Gênica / Dicumarol / DNA Circular / Transativadores / Vírus da Hepatite B / NAD(P)H Desidrogenase (Quinona) / Hepatite B Crônica / Proteínas Virais Reguladoras e Acessórias / Proteólise Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Holanda