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Aß-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice.
Cuddy, Leah K; Prokopenko, Dmitry; Cunningham, Eric P; Brimberry, Ross; Song, Peter; Kirchner, Rory; Chapman, Brad A; Hofmann, Oliver; Hide, Winston; Procissi, Daniele; Hanania, Taleen; Leiser, Steven C; Tanzi, Rudolph E; Vassar, Robert.
Afiliação
  • Cuddy LK; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Prokopenko D; Genetics and Aging Unit and McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, USA.
  • Cunningham EP; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Brimberry R; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Song P; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Kirchner R; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  • Chapman BA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  • Hofmann O; Department of Clinical Pathology, University of Melbourne, Victoria 3000, Melbourne, Australia.
  • Hide W; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Procissi D; Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Hanania T; PsychoGenics Inc., Paramus, NJ 07652, USA.
  • Leiser SC; PsychoGenics Inc., Paramus, NJ 07652, USA.
  • Tanzi RE; Genetics and Aging Unit and McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, USA. r-vassar@northwestern.edu tanzi@helix.mgh.harvard.edu.
  • Vassar R; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. r-vassar@northwestern.edu tanzi@helix.mgh.harvard.edu.
Sci Transl Med ; 12(563)2020 09 30.
Article em En | MEDLINE | ID: mdl-32998969
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos