Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis.

Guo, Jiayan; Mei, Hanbing; Sheng, Zhen; Meng, Qingyuan; Véniant, Murielle M; Yin, Hong

Guo, Jiayan; Mei, Hanbing; Sheng, Zhen; Meng, Qingyuan; Véniant, Murielle M; Yin, Hong.

Afiliação

Guo J; Amgen Biopharmaceutical Research and Development (Shanghai) Co., Ltd., Shanghai, China.
Mei H; Amgen Biopharmaceutical Research and Development (Shanghai) Co., Ltd., Shanghai, China.
Sheng Z; Amgen Biopharmaceutical Research and Development (Shanghai) Co., Ltd., Shanghai, China.
Meng Q; Amgen Biopharmaceutical Research and Development (Shanghai) Co., Ltd., Shanghai, China.
Véniant MM; Department of Cardiometabolic Disorders, Amgen Research, Amgen Inc., Thousand Oaks, CA, USA. Electronic address: mveniant@amgen.com.
Yin H; Amgen Biopharmaceutical Research and Development (Shanghai) Co., Ltd., Shanghai, China. Electronic address: yinh@amgen.com.

J Lipid Res ; 61(12): 1764-1775, 2020 12.

Article em En | MEDLINE | ID: mdl-33008925

Assuntos

Aterosclerose/genética; Aterosclerose/patologia; MicroRNAs/genética; Animais; Apoptose; Modelos Animais de Doenças; Células Endoteliais/patologia; Feminino; Camundongos; Transdução de Sinais

Palavras-chave

animal model; apoptosis; endothelial cells; familial hypercholesterolemia; inflammation; low density lipoprotein receptor; micro-ribonucleic acid; tumor necrosis factor α-induced protein 3

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Aterosclerose Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Lipid Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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