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Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity.
Heindel, Daniel W; Koppolu, Sujeethraj; Zhang, Yue; Kasper, Brian; Meche, Lawrence; Vaiana, Christopher A; Bissel, Stephanie J; Carter, Chalise E; Kelvin, Alyson A; Elaish, Mohamed; Lopez-Orozco, Joaquin; Zhang, Bin; Zhou, Bin; Chou, Tsui-Wen; Lashua, Lauren; Hobman, Tom C; Ross, Ted M; Ghedin, Elodie; Mahal, Lara K.
Afiliação
  • Heindel DW; Biomedical Research Institute, Department of Chemistry, New York University, New York, NY 10003.
  • Koppolu S; Biomedical Research Institute, Department of Chemistry, New York University, New York, NY 10003.
  • Zhang Y; Biomedical Research Institute, Department of Chemistry, New York University, New York, NY 10003.
  • Kasper B; Biomedical Research Institute, Department of Chemistry, New York University, New York, NY 10003.
  • Meche L; Biomedical Research Institute, Department of Chemistry, New York University, New York, NY 10003.
  • Vaiana CA; Biomedical Research Institute, Department of Chemistry, New York University, New York, NY 10003.
  • Bissel SJ; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.
  • Carter CE; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30602.
  • Kelvin AA; Department of Pediatrics, Dalhousie University, Halifax, NS, B3H 4R2, Canada.
  • Elaish M; Department of Cell Biology, University of Alberta, Edmonton, AB, T6G 2R7, Canada.
  • Lopez-Orozco J; Poultry Diseases Department, Faculty of Veterinary Medicine, Cairo University, Cairo, 12211, Egypt.
  • Zhang B; High Content Analysis Core, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB, T6G 2R7, Canada.
  • Zhou B; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Chou TW; Center for Genomics & Systems Biology, Department of Biology, New York University, New York, NY 10003.
  • Lashua L; Center for Genomics & Systems Biology, Department of Biology, New York University, New York, NY 10003.
  • Hobman TC; Center for Genomics & Systems Biology, Department of Biology, New York University, New York, NY 10003.
  • Ross TM; Department of Cell Biology, University of Alberta, Edmonton, AB, T6G 2R7, Canada.
  • Ghedin E; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30602.
  • Mahal LK; Center for Genomics & Systems Biology, Department of Biology, New York University, New York, NY 10003.
Proc Natl Acad Sci U S A ; 117(43): 26926-26935, 2020 10 27.
Article em En | MEDLINE | ID: mdl-33046650

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Influenza Humana / Interações Hospedeiro-Patógeno / Pulmão / Manose Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Influenza Humana / Interações Hospedeiro-Patógeno / Pulmão / Manose Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos