MiR-193b modulates osteoarthritis progression through targeting ST3GAL4 via sialylation of CD44 and NF-ÐºB pathway.

Wang, Tianfu; Hao, Zhiyu; Liu, Changcheng; Yuan, Lebin; Li, Li; Yin, Menghong; Li, Qing; Qi, Zhiming; Wang, Zi

Wang, Tianfu; Hao, Zhiyu; Liu, Changcheng; Yuan, Lebin; Li, Li; Yin, Menghong; Li, Qing; Qi, Zhiming; Wang, Zi.

Afiliação

Wang T; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China; Department of Spinal Surgery, The Second Hospital of Dalian Medical University, Dalian 116033, Liaoning Province, China.
Hao Z; Department of Imaging and Nuclear Medicine, The Second Hospital of Dalian Medical University, Dalian 116033, Liaoning Province, China.
Liu C; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China.
Yuan L; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China.
Li L; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China.
Yin M; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China.
Li Q; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China.
Qi Z; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China.
Wang Z; Department of Sports Medicine, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China. Electronic address: dlwangzi0815@163.com.

Cell Signal ; 76: 109814, 2020 12.

Article em En | MEDLINE | ID: mdl-33080315

Assuntos

Receptores de Hialuronatos/metabolismo; MicroRNAs/fisiologia; NF-kappa B/metabolismo; Osteoartrite/metabolismo; Sialiltransferases/metabolismo; Adulto; Animais; Estudos de Casos e Controles; Células Cultivadas; Condrócitos; Humanos; Ratos Sprague-Dawley

Palavras-chave

CD44; NF-ÐºB signaling pathway; Osteoarthritis; ST3GAL4; miR-193b

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Sialiltransferases / NF-kappa B / Receptores de Hialuronatos / MicroRNAs Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Humans Idioma: En Revista: Cell Signal Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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