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Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.
Zhang, Baole; Pang, Luping; Nautiyal, Manesh; De Graef, Steff; Gadakh, Bharat; Lescrinier, Eveline; Rozenski, Jef; Strelkov, Sergei V; Weeks, Stephen D; Van Aerschot, Arthur.
Afiliação
  • Zhang B; Rega Institute for Medical Research, Medicinal Chemistry, KU Leuven, Herestraat 49-box 1041, 3000 Leuven, Belgium.
  • Pang L; Rega Institute for Medical Research, Medicinal Chemistry, KU Leuven, Herestraat 49-box 1041, 3000 Leuven, Belgium.
  • Nautiyal M; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49-box 822, 3000 Leuven, Belgium.
  • De Graef S; Rega Institute for Medical Research, Medicinal Chemistry, KU Leuven, Herestraat 49-box 1041, 3000 Leuven, Belgium.
  • Gadakh B; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49-box 822, 3000 Leuven, Belgium.
  • Lescrinier E; Rega Institute for Medical Research, Medicinal Chemistry, KU Leuven, Herestraat 49-box 1041, 3000 Leuven, Belgium.
  • Rozenski J; Rega Institute for Medical Research, Medicinal Chemistry, KU Leuven, Herestraat 49-box 1041, 3000 Leuven, Belgium.
  • Strelkov SV; Rega Institute for Medical Research, Medicinal Chemistry, KU Leuven, Herestraat 49-box 1041, 3000 Leuven, Belgium.
  • Weeks SD; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49-box 822, 3000 Leuven, Belgium.
  • Van Aerschot A; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49-box 822, 3000 Leuven, Belgium.
Molecules ; 25(20)2020 Oct 16.
Article em En | MEDLINE | ID: mdl-33081246
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleosídeos / Benzimidazóis / Inibidores Enzimáticos / Aminoacil-tRNA Sintetases Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleosídeos / Benzimidazóis / Inibidores Enzimáticos / Aminoacil-tRNA Sintetases Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Suíça