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First-in-class humanized FSH blocking antibody targets bone and fat.
Gera, Sakshi; Sant, Damini; Haider, Shozeb; Korkmaz, Funda; Kuo, Tan-Chun; Mathew, Mehr; Perez-Pena, Helena; Xie, Honglin; Chen, Hao; Batista, Rogerio; Ma, Kejun; Cheng, Zhen; Hadelia, Elina; Robinson, Cemre; Macdonald, Anne; Miyashita, Sari; Williams, Anthony; Jebian, Gregory; Miyashita, Hirotaka; Gumerova, Anisa; Ievleva, Kseniia; Smith, Pinar; He, Jiahuan; Ryu, Vitaly; DeMambro, Victoria; Quinn, Matthew A; Meseck, Marcia; Kim, Se-Min; Kumar, T Rajendra; Iqbal, Jameel; New, Maria I; Lizneva, Daria; Rosen, Clifford J; Hsueh, Aaron J; Yuen, Tony; Zaidi, Mone.
Afiliação
  • Gera S; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Sant D; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Haider S; Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, WC1N 1AX London, United Kingdom.
  • Korkmaz F; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Kuo TC; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Mathew M; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Perez-Pena H; Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, WC1N 1AX London, United Kingdom.
  • Xie H; GenScript Biotech Corporation, Piscataway, NJ 08854.
  • Chen H; Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University, Stanford, CA 94305.
  • Batista R; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Ma K; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Cheng Z; Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, Gansu 730030, China.
  • Hadelia E; Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University, Stanford, CA 94305.
  • Robinson C; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Macdonald A; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Miyashita S; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Williams A; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Jebian G; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Miyashita H; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Gumerova A; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Ievleva K; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Smith P; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • He J; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Ryu V; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305.
  • DeMambro V; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Quinn MA; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME 04074.
  • Meseck M; Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC 27157.
  • Kim SM; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Kumar TR; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Iqbal J; Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO 80045.
  • New MI; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Lizneva D; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029 maria.new@mssm.edu mone.zaidi@mssm.edu.
  • Rosen CJ; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
  • Hsueh AJ; Center for Clinical and Translational Research, Maine Medical Center Research Institute, Scarborough, ME 04074.
  • Yuen T; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305.
  • Zaidi M; The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Proc Natl Acad Sci U S A ; 117(46): 28971-28979, 2020 11 17.
Article em En | MEDLINE | ID: mdl-33127753
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osso e Ossos / Tecido Adiposo / Anticorpos Bloqueadores / Hormônio Foliculoestimulante / Epitopos Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osso e Ossos / Tecido Adiposo / Anticorpos Bloqueadores / Hormônio Foliculoestimulante / Epitopos Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de publicação: Estados Unidos