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A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.
Sievers, Philipp; Sill, Martin; Schrimpf, Daniel; Stichel, Damian; Reuss, David E; Sturm, Dominik; Hench, Jürgen; Frank, Stephan; Krskova, Lenka; Vicha, Ales; Zapotocky, Michal; Bison, Brigitte; Castel, David; Grill, Jacques; Debily, Marie-Anne; Harter, Patrick N; Snuderl, Matija; Kramm, Christof M; Reifenberger, Guido; Korshunov, Andrey; Jabado, Nada; Wesseling, Pieter; Wick, Wolfgang; Solomon, David A; Perry, Arie; Jacques, Thomas S; Jones, Chris; Witt, Olaf; Pfister, Stefan M; von Deimling, Andreas; Jones, David T W; Sahm, Felix.
Afiliação
  • Sievers P; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Sill M; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Schrimpf D; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Stichel D; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Reuss DE; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Sturm D; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Hench J; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Frank S; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Krskova L; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Vicha A; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Zapotocky M; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Bison B; Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Castel D; Department of Pediatric Oncology, Hematology, Immunology, and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany.
  • Grill J; Institute for Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
  • Debily MA; Institute for Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
  • Harter PN; Prague Brain Tumor Research Group, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
  • Snuderl M; Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
  • Kramm CM; Prague Brain Tumor Research Group, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
  • Reifenberger G; Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
  • Korshunov A; Prague Brain Tumor Research Group, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
  • Jabado N; Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
  • Wesseling P; Institute of Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Würzburg, Germany.
  • Wick W; Molecular Predictors and New Targets in Oncology, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
  • Solomon DA; Département de Cancérologie de l'Enfant et de l'Adolescent, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
  • Perry A; Molecular Predictors and New Targets in Oncology, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
  • Jacques TS; Département de Cancérologie de l'Enfant et de l'Adolescent, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
  • Jones C; Molecular Predictors and New Targets in Oncology, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
  • Witt O; Département de Biologie, Univ. Evry, Université Paris-Saclay, Evry, France.
  • Pfister SM; Institute of Neurology (Edinger Institute), Goethe University, Frankfurt am Main, Germany.
  • von Deimling A; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, Germany.
  • Jones DTW; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Sahm F; Frankfurt Cancer Institute (FCI), Frankfurt am Main, Germany.
Neuro Oncol ; 23(1): 34-43, 2021 01 30.
Article em En | MEDLINE | ID: mdl-33130881
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioma Tipo de estudo: Prognostic_studies Limite: Child / Humans Idioma: En Revista: Neuro Oncol Assunto da revista: NEOPLASIAS / NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioma Tipo de estudo: Prognostic_studies Limite: Child / Humans Idioma: En Revista: Neuro Oncol Assunto da revista: NEOPLASIAS / NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido