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The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects.
Broekaart, Diede Wm; Bertran, Alexandra; Jia, Shaobo; Korotkov, Anatoly; Senkov, Oleg; Bongaarts, Anika; Mills, James D; Anink, Jasper J; Seco, Jesús; Baayen, Johannes C; Idema, Sander; Chabrol, Elodie; Becker, Albert J; Wadman, Wytse J; Tarragó, Teresa; Gorter, Jan A; Aronica, Eleonora; Prades, Roger; Dityatev, Alexander; van Vliet, Erwin A.
Afiliação
  • Broekaart DW; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Bertran A; Accure Therapeutics S.L., Barcelona, Spain.
  • Jia S; Molecular Neuroplasticity Group, German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
  • Korotkov A; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Senkov O; Molecular Neuroplasticity Group, German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
  • Bongaarts A; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Mills JD; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Anink JJ; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Seco J; Accure Therapeutics S.L., Barcelona, Spain.
  • Baayen JC; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Neurosurgery, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Idema S; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Neurosurgery, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Chabrol E; UCL Institute of Neurology, University College London, London, United Kingdom.
  • Becker AJ; Section for Translational Epilepsy Research, Department of Neuropathology, University of Bonn Medical Center, Bonn, Germany.
  • Wadman WJ; Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Amsterdam, Netherlands.
  • Tarragó T; Accure Therapeutics S.L., Barcelona, Spain.
  • Gorter JA; Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Amsterdam, Netherlands.
  • Aronica E; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, Netherlands.
  • Prades R; Stichting Epilepsie Instellingen Nederland (SEIN), Heemstede, Netherlands.
  • Dityatev A; Accure Therapeutics S.L., Barcelona, Spain.
  • van Vliet EA; Molecular Neuroplasticity Group, German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
J Clin Invest ; 131(1)2021 01 04.
Article em En | MEDLINE | ID: mdl-33141761
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estado Epiléptico / Encéfalo / Epilepsia do Lobo Temporal / Inibidores de Metaloproteinases de Matriz Limite: Animals / Female / Humans / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estado Epiléptico / Encéfalo / Epilepsia do Lobo Temporal / Inibidores de Metaloproteinases de Matriz Limite: Animals / Female / Humans / Male Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda País de publicação: Estados Unidos